Totally this I read an absolute ton (and more even if you count audio books, which I do) and the vast majority is from the library. Even easier now with ebooks and apps. I’ve still got a pretty full bookshelf though of things like Illustrated editons, some real nice printings of some of my favorites, older books, and comics/graphic novels.

First I’m very sorry about your dog.

I don’t know as much of the veterinary world. And there’s a ton of information your vet and surgeon has on your specific case that no one online will have, so no one here is going to give you very specific answers to your case. So take everything that follows with a grain of salt, and talk more with your surgeon, not internet strangers. And it sounds like your dog was in a very dangerous situation, keep in mind a bad outcome doesn’t necessarily mean anyone did anything wrong, you and your surgeon included. I can tell you some general things about how repurfusion can be dangerous in humans though.

I was confused why both your explanations are hung up on free radicals. Not that there aren’t, I’m guessing there’d be more than usual. It’s just a bizarre explanation of repurfusion injury. There’s many dangers, but basically if you have dead or poorly perfused tissue (sounds like there was a lot of this from your description), and there’s a turniket or a hernia acting as a turniket in this case squeezing the blood supply so nothing is getting in or out, or very little is getting in or out, all of the harmful dead stuff from the process of that tissue dying is somewhat stuck there. But once this narrowing is resolved (taking off a turniket or getting the tissue out of the henria in this case) now there’s blood flow and all the material form this dying or dead tissue has a clear route back to the rest of the body. It also sound like in this case there was a really horrific large hernia with probably multiple sections of multiple organs that had already infarcted (died from lack of oxygen/blood flow) based on what you wrote. Sometimes in humans you can resect small portions of dead intestine and reconnect remaining pieces, but you can’t just take out their whole liver, they need that.

But free radicals is a weird red herring thing to talk about. Potassium is the main killer for repurfusion injury. There’s very little potassium outside cells (like in your blood and fluids), but tons inside cells. Well we have a whole mass of tissue from multiple organs that just died and that’s all getting released at once. The heart does not like this, and can go into arrhythmias and stop beating. Potassium is actually the final drug used in a lethal injection in capital punishment for instance. There’s tons of other harmful things going on too. But if large sections of multiple orgams had already died or been severely injured by the hernia, there may not have been any possible way to save them. And if you leave them that way the harmful stuff will find it’s way out eventually anyways, and the dead gi organs will cause massive septic shock as all the bacteria spill out from the inner gut through all the dead tissue into the rest of the body. Long story short, ischemia or infarction of bowels and other gi organs from a hernia or any other cause is an extremely dangerous situation requiring emergency surgery and can be fatal in humans, and even with that it may be impossible to save them. I’m guessing it’s similar for dogs.

Again take everything I said with a grain of salt, your surgeon has the best information on what actually happened. I just wouldn’t get too hung up on “free radicals.” Ischemic or infarcted orgams is an extremely dangerous situation for tons of reasons.

Yeah I feel you, the green party has some good positions. But then they go ahead and nominate people like Jill Stein, who has some good but many horrible foreign policy ideas like ending NATO and allowing Russia to do whatever it wants to eastern European countries. In climate areas has relatively good positions, but then despite claiming to follow science she will constantly reject it when it comes to her own bizarre theories about vaccines, banning wifi from areas with children, or trying to ban gmos that have extensive evidence for safety until they meet some arbitrary threshold in her own head and scientists prove a negative, which is impossible. Not to mention what that would do to food prices and create widespread shortages and hunger and cause actual harm around the world if she got her way.

I’d love viable third parties, but they’ve been picking terrible candidates lately, so I don’t really see the appeal atm. I think the path forward there is being active in primaries and pushing candidates forward in the main parties forward who support alternative voting systems like rank choice. Otherwise while we still have first past the post voting, any but the main two parties is never really going to be viable and will probably just end up being counterproductive to their own stated goals.

Not a specific community, but check out everything on mander.xyz if you haven’t yet. Lots of great science related communities on there. It’s already a pretty active instance but would love to see the communities on there get even more love.

Alright, we’ll just rip the implants keeping patients seizure free out of their heads and tell everyone with Parkinson’s sorry, brain implants have to be removed now, go back to being frozen. Saying we can’t use a technology because someone might do something bad with it someday could apply to literally any technology.

Or are you proposing getting rid of legal frameworks and regulation of medications would improve them somehow? Just let big pharma go realky wild? Strengthen our regulatory frameworks by all means, stop regulatory capture and all that, but an unbridled free for all with big pharma allowed to do, sell, and say whatever it wants about its products sounds horrific. I think you’re right to think the fda may have gotten a little too lenient with some approvals lately, but that’s an argument for stengthening the regulations not getting rid of them.

But yeah Elon isn’t allowed to sell this shit yet, and people have to elect to be involved in any trials. It’s their choice. If he ever tries to sell it, he’ll have to prove efficacy and safety. Without that regulatory framework he wouldn’t need to do even that, could just immediately launch it and lie about the capabilities a la tesla auto pilot, duping and killing a bunch of people likely.

Yeah, what is this meme? Like I get Elon is a douche. But I mean where do people think deep brain simulation and things that help tons of people already come from? We even have implantable devices that can record seizures directly from the brain surface and generate electric impulses to disrupt them. Not to mention pacemakers, spinal cord stimulators, etc. All these things have quite a lot of regulatory hurdles before reaching market. Obviously want to make sure that framework stays strong so no dystopian nonsense down the line happens. Once we get to the level of consumer grade brainchips, then I’ll start to worry.

Big citation needed on “most” co2 reductions come from carbon capture. If you have it I’d be interested, I couldn’t find anything suggesting that. It’s a huge bill that carbon capture is just one small part of. I do agree in most circumstances it’s talked about right now it’s a bit of a scam, especially the idea you’re going to be able to pull it out of the air at very low concentrations. Capturing carbon from existing fossil fuel facilities where the concentration may be much higher (something like 13% in many cases as opposed to like 0.04% in normal air) is something more worth exploring. Unless you’re suggesting all fossil fuel facilities shut down overnight, exploring ways to make facilities release less carbon is important. The cited article makes a big point about how the power plant emitted more than it captured. But how much would it have emitted without any capture it conspicuously leaves out. Without any capture it would emit more I would assume. Certainly it sounds like those Shell executives lied about how much it was capturing and the US needs to do more, not disagreeing there.

The inflation reduction act was still the most impactful climate act ever passed. You can argue to do more without pretending it was nothing. Dems wanted to do more as well, a lot of these compromises were to get one last senator to come along, and if we had more Dems in the senate they wouldn’t have done it. Or even a single fucking republican out of any of them of course who doesn’t want to actively destroy the earth. Save the most vicious attacks for the ones who deserve it most, not the ones actually trying to do something.

Oh didn’t mean to imply they’re not greedy, it’s a company. Nvidia would be far greedier though then unless you value their extra features with otherwise worse performance by that much more money. And without competition Nvidia would have free reign to get even more absurd in their pricing. Some competition is better than none. Maybe Intel gpus will start getting good and we can really get some competition going to drive prices lower hopefully.

Yeah agree the high range for amd is meh, if you’re just looking for the best out there money is no object, fine with >$1000 gpus, Nvidia has no competition there. The 7900s are more competitive with the Nvidia 4080s and undercut those on price too, 4080s are $1200. So they should really be looked at as a 4080 alternative not 4090 which has no real alternative. Amd offers nothing nearly as expensive as a 4090.

Im very interested in the 7800xt which is a 4070 competitor. If it’s outperforming the 4070 in most respects like the amd numbers suggests I think it’ll be a great value since it’s $100 cheaper. The 4070 only having 12 gb of vram is pretty disappointing too for future proofing, especially for the price. Would like to wait on the reviews of the 7800xt of course first, we only have company provided numbers so far. Also interested in their progress on ray tracing and fsr, which they’ve clearly been behind Nvidia on for a number of years. But getting enough fps and achieving the resolution you want should still be priority number one over something more niche and game dependent like ray tracing when you’re picking out a card I think.

Maybe, because cpu wise amd should be doing better than intel on heat and power consumption. Loud would have to do with the cooler you choose and wouldn’t be a function of the cpu itself. Aftermarket coolers are often better than stock and not that pricey, but will want to look into reviews for a quiet one. Amd had been cleaning intel’s clock the past few generations in cpu performance. Intel has finally caught up again and is slightly ahead in power this gen, though amd still winning a lot in efficiency and power consumption/heat and still has the best gaming cpu. Good summary here.

https://www.tomshardware.com/features/amd-vs-intel-cpus

In terms of gpu that’s gonna vary widely depending on what specific gpu and what configuration of that gpu you’re buying. Before buying I would look into specific reviews of that manufacturer if you can and not just the stock gpu itself, because every one is going to have a different configuration and fan/cooler setup for the gpu. Unfortunately gpus from both amd and Nvidia are becoming more and more power hungry giant heat generating monsters over time.

Not really. Since we don’t have the ability to instance block ourselves yet I changed instances to one not federating with them to avoid them and similar authoritarian instances like lemmygrad and exploding heads. I swing pretty far left on the political spectrum myself, but there’s a difference between that and simping for dictators, genocide denial, and other problematic things. I don’t even get it, China and Russia can hardly be described as leftist by any definition but they’ll bend over backwards to defend anything they do, and try to change the subject to another country instead if they can’t.

Yeah I was using lemm.ee but the hexbear spam in the threads was ridiculous. They were swarming the meta thread discussing defederating them too, and it seemed like the instance admin was determined to keep federating with them. Went on the hunt to join a popular instance that doesn’t federate with them. There’s a few out there that do block the annoying authoritarian/boot-licking trifecta of lemmygrad, explodingheads, and hexbear. Sopuli.xyz was the one I ended up joining.